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OGT Regulates Hematopoietic Stem Cell Maintenance via PINK1-Dependent Mitophagy
Authors:Koichi Murakami  Daisuke Kurotaki  Wataru Kawase  Shunsuke Soma  Yumi Fukuchi  Hiroyoshi Kunimoto  Ryusuke Yoshimi  Shuhei Koide  Motohiko Oshima  Takako Hishiki  Noriyo Hayakawa  Tomomi Matsuura  Mayumi Oda  Kiichi Yanagisawa  Hiroshi Kobayashi  Miho Haraguchi  Yoshitoshi Atobe  Kengo Funakoshi  Hideaki Nakajima
Affiliation:1. Division of Hematology, Department of Internal Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan;2. Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan;3. Advanced Medical Research Center, Yokohama City University, Yokohama 236-0004, Japan;4. Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan;5. Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan;6. Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8039, Japan;7. Clinical and Translational Research Center, Keio University School of Medicine, Tokyo 160-8582, Japan;8. Department of Biochemistry, Keio University School of Medicine, Tokyo 160-8582, Japan;9. Department of Systems Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan;10. Department of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan;11. Department of Neuroanatomy, Yokohama City University School of Medicine, Yokohama 236-0004, Japan
Abstract:
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  • Keywords:OGT  hematopoietic stem cell  hematopoietic progenitor cell  mitochondria  mitophagy  PINK1
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