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Attenuation of Antiviral Immune Response Caused by Perturbation of TRIM25-Mediated RIG-I Activation under Simulated Microgravity
Authors:Lvyun Zhu  Li Nie  Sisi Xie  Ming Li  Chushu Zhu  Xinyuan Qiu  Jingyu Kuang  Chuanyang Liu  Chenyu Lu  Wenying Li  Er Meng  Dongyi Zhang  Lingyun Zhu
Affiliation:1. Department of Biology and Chemistry, College of Liberal Arts and Sciences, National University of Defense Technology, Changsha, Hunan, P.R. China;2. State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, School of Marine Sciences, Ningbo University, Ningbo, P.R. China
Abstract:
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  • Keywords:simulated microgravity  rotary cell culture system  zebrafish embryo model  antiviral immunity  TRIM25  RIG-I  type I interferon  K63-linked ubiquitination  positive feedback loop
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