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Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis
Authors:Kshiti Phulphagar  Lars I. Kühn  Stefan Ebner  Annika Frauenstein  Jonathan J. Swietlik  Jan Rieckmann  Felix Meissner
Affiliation:1. Experimental Systems Immunology Laboratory, Max Planck Institute of Biochemistry, Martinsried, Germany;2. Institute of Innate Immunity, Department of Systems Immunology and Proteomics, Medical Faculty, University of Bonn, Bonn, Germany
Abstract:
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  • Keywords:pyroptosis  gasdermin D  macrophage  protein secretion  secretome  mass spectrometry  proteomics  NLRP3  TLR4  cell death
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