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Global non-covalent SUMO interaction networks reveal SUMO-dependent stabilization of the non-homologous end joining complex
Authors:Román González-Prieto  Karolin Eifler-Olivi  Laura A. Claessens  Edwin Willemstein  Zhenyu Xiao  Cami M.P. Talavera Ormeno  Huib Ovaa  Helle D. Ulrich  Alfred C.O. Vertegaal
Affiliation:1. Department of Cell and Chemical Biology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, the Netherlands;2. Institute of Molecular Biology (IMB), Ackermannweg 4, 55128 Mainz, Germany;3. Oncode Institute, Einthovenweg 20, 2333 ZC Leiden, the Netherlands
Abstract:
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  • Keywords:small ubiquitin-like modifier  SUMO  SUMO1  SUMO2  SUMO Interaction Motif  chain  ubiquitin  mass spectrometry  non-homologous end joining  DNA damage response
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