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The autism-related protein CHD8 contributes to the stemness and differentiation of mouse hematopoietic stem cells
Authors:Akihiro Nita  Yoshiharu Muto  Yuta Katayama  Akinobu Matsumoto  Masaaki Nishiyama  Keiichi I. Nakayama
Affiliation:1. Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Fukuoka 812-8582, Japan
Abstract:
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  • Keywords:hematopoietic stem cell  CHD8  p53  differentiation block  stemness  chromatin remodeler  cell cycle arrest  apoptosis  colony formation assay  bone marrow transplantation
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