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Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex
Authors:John K. Mich  Lucas T. Graybuck  Erik E. Hess  Joseph T. Mahoney  Yoshiko Kojima  Yi Ding  Saroja Somasundaram  Jeremy A. Miller  Brian E. Kalmbach  Cristina Radaelli  Bryan B. Gore  Natalie Weed  Victoria Omstead  Yemeserach Bishaw  Nadiya V. Shapovalova  Refugio A. Martinez  Olivia Fong  Shenqin Yao  Boaz P. Levi
Affiliation:1. Allen Institute for Brain Science, Seattle, WA, USA;2. Washington National Primate Research Center, University of Washington, Seattle, WA, USA;3. Department of Biology and Applied Physics, Stanford University, Stanford, CA, USA;4. The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment, Swedish Neuroscience Institute, Seattle, WA, USA;5. Department of Neurological Surgery, University of Washington School of Medicine, Seattle, WA, USA;6. Regional Epilepsy Center, Harborview Medical Center, Seattle, WA, USA;7. Department of Pathology, University of Washington, Seattle, WA, USA;8. Department of Neurological Surgery and Alvord Brain Tumor Center, University of Washington, Seattle, WA, USA;9. Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA;10. Department of Physiology and Biophysics, University of Washington, Seattle, WA, USA;11. Epilepsy Surgery and Functional Neurosurgery, Swedish Neuroscience Institute, Seattle, WA, USA
Abstract:
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  • Keywords:human  macaque  brain cell types  epigenetics  enhancers  AAVs  genetic tools  ATAC-seq  parvalbumin
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