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Cell-Type-Specific Immune Dysregulation in Severely Ill COVID-19 Patients
Authors:Changfu Yao  Stephanie A. Bora  Tanyalak Parimon  Tanzira Zaman  Oren A. Friedman  Joseph A. Palatinus  Nirmala S. Surapaneni  Yuri P. Matusov  Giuliana Cerro Chiang  Alexander G. Kassar  Nayan Patel  Chelsi E.R. Green  Adam W. Aziz  Harshpreet Suri  Jo Suda  Andres A. Lopez  Gislâine A. Martins  Barry R. Stripp  Peter Chen
Affiliation:1. Women’s Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA;2. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA;3. Department of Biomedical Sciences, Research Division of Immunology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA;4. F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA;5. Division of Gastroenterology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA;6. Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA;7. Computational Medicine Core at Center for Lung Biology, Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, WA 98109, USA
Abstract:
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  • Keywords:acute respiratory distress syndrome  ARDS  coronavirus disease 2019  COVID-19  severe acute respiratory syndrome coronavirus 2  SARS-CoV-2  single-cell RNA sequencing  network analysis
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