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Single-cell resolved imaging reveals intra-tumor heterogeneity in glycolysis,transitions between metabolic states,and their regulatory mechanisms |
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| Authors: | Hiroshi Kondo Colin DH Ratcliffe Steven Hooper James Ellis James I MacRae Marc Hennequart Christopher W Dunsby Kurt I Anderson Erik Sahai |
| Institution: | 1. Tumor Cell Biology Laboratory, The Francis Crick Institute, London, NW1 1AT, UK;2. Metabolomics Science Technology Platform, The Francis Crick Institute, London, NW1 1AT, UK;3. p53 and Metabolism Laboratory, The Francis Crick Institute, London, NW1 1AT, UK;4. Photonics Group, Physics Department, Imperial College London, London, SW7 2AZ, UK;5. Crick Advanced Light Microscopy Facility, The Francis Crick Institute, London, NW1 1AT, UK |
| Abstract: |  |
| Keywords: | FRET imaging intra-tumor heterogeneity tumor metabolism intravital imaging cofilin PI3K signaling breast cancer |
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