GOlorize: a Cytoscape plug-in for network visualization with Gene Ontology-based layout and coloring |
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| Authors: | Garcia Olivier Saveanu Cosmin Cline Melissa Fromont-Racine Micheline Jacquier Alain Schwikowski Benno Aittokallio Tero |
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| Institution: | Systems Biology Unit, Institut Pasteur, 75724 Paris Cedex 15, France. |
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| Abstract: | We have implemented a graph layout algorithm that exposes Gene Ontology (GO) class structure on the network nodes. It can be used in conjunction with BiNGO plug-in to Cytoscape, which finds the GO categories over-represented in a given network. Our plug-in, named GOlorize, first highlights the class members with category-specific color-coding and then constructs an enhanced visualization of the network using a class-directed layout algorithm. Availability: http://www.cytoscape.org/plugins2.php. Supplementary information: Installation instructions and tutorial at http://www.cytoscape.org/plugins/GOlorize/GOlorizeUserGuide.pdf. |
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