A human liposarcoma cell line |
| |
| Authors: | E Bey I M Spence J J Alexander K Robinson R Bernstein |
| |
| Institution: | (1) Virus Cancer Research Unit, National Institute for Virology, 2131, Private Bag X4 Johannesburg, South;(2) Department of Physiology, Medical School, University of Natal, 4013 Durban, South;(3) Department of Human Genetics, School of Pathology, S. A. Institute for Medical Research, 2001 Johannesburg, South Africa;(4) University of the Witwatersrand, 2001 Johannesburg, South Africa |
| |
| Abstract: | Summary The properties of a new cell line derived from a human retroperitoneal liposarcoma are described. The cells do not grow at
low cell concentrations and contain in their cytoplasm large numbers of droplets that stain with Oil Red O. No indication
of the presence of endogenous virus particles could be found. The mean chromosome number per cell is 36, with several constant
markers, the most conspicuous of which is a large submetacentric marker due to a translocation between chromosomes 4 and 11,
which is present in every cell. The liposarcoma cells show an enhanced uptake of 14C]acetate compared to normal human fibroblasts.
This work was supported by funds from the Poliomyelitis Research Foundation, the National Cancer Association of South Africa,
and the State health Department. The authors thank Mrs. D. Bower and Mrs. M. Orchard for their excellent technical assistance. |
| |
| Keywords: | liposarcoma cell culture chromosomes acetate metabolism |
| 本文献已被 SpringerLink 等数据库收录！ |
|
