A breakdown in macromolecular synthesis preceding differentiation in Streptomyces coelicolor A3(2). |
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| Authors: | C Granozzi R Billetta R Passantino M Sollazzo A M Puglia |
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| Affiliation: | Dipartimento di Biologia Cellulare e dello Sviluppo, Sezione di Genetica, Università di Palermo, Italy. |
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| Abstract: | A transitory cessation of growth was recorded in Streptomyces coelicolor A3(2) at the end of vegetative mycelium formation on solid medium. In the same phase a striking reduction in protein and nucleic acid synthesis was detected. Growth and macromolecular synthesis resumed, nearly reaching the original values, when morphological differentiation occurred. It is concluded that a physiological stress occurs within the bacterial population just before the onset of the morphological differentiation. |
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