Role of secondary phosphoinositide messengers in storage of Ca2+ ions in retinal rod microsomes |
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Authors: | Emel'ianova V P Baranova L A Volotovski? I D |
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Institution: | Institute of Photobiology, Belorussian Academy of Sciences, ul. Academicheskaya 27, Minsk, 220072 Belarus. |
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Abstract: | The influence of guanosine-5'-triphosphate and secondary messengers forming in rod outer segment membranes during light-stimulated hydrolysis of phosphoinositides on the ATP-dependent Ca(2+)-uptake in microsomes of the retinal rod inner segment was studied. The water-soluble cytoplasmic components of the retinal rod outer segment were shown to be capable of stimulating the Ca(2+)-pump of endoplasmic reticulum after light illumination. This process is likely to proceed with the participation of 1,2-diacylglycerol localized in microsome membrane. |
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