Ionone,iridoid and phenylethanoid glycosides from Ajuga salicifolia

From the aerial parts of Ajuga salicifolia (L.) Schreber, a new ionone glycoside (3beta-hydroxy-7,8-dihydro-4-oxo-beta-ionol-9-O-beta-D-glucopyranoside) was isolated, along with the known compounds, corchoionoside C, 8-O-acetylmioporoside, ajugol, harpagide, 8-O-acetylharpagide, lavandulifolioside and leonosides A and B. This is the first report of the occurrence of ionone glycosides and 8-O-acetylmioporoside in Ajuga species. Ajugol, lavandulifolioside, leonoside A and B were isolated for the first time from Ajuga salicifolia. The structures were elucidated by means of 1D-, 2D-NMR spectroscopy, and HR-MALDI mass spectrometry.