Influence of prostaglandin F2α on sperm production and seminal characteriticss of the stallion |
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Authors: | JL Kreider WL Ogg JW Turner |
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Institution: | Department of Animal Science Louisiana State University, Baton Rouge, Louisiana 70803, USA |
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Abstract: | Six mature stallions were used to test the effect of prostaglandin F2α (PGF2α) on sperm production and seminal characteristics. Semen was collected from each stallion twice weekly 1 hr following a 10 mg intramuscular injection of PGF2α or a sham injection. A switchback design was used so that three stallions received PGF2 and three served as controls during the first 9 weeks (period 1). Threatment regimens were reversed during the second 9 weeks (period 2). Treatment of stallions with PGF2α resulted in an increase (/prmP<.05) in gel free seminla voume and a decrease in sperm cell concentration. Total spermatozoa, sperm cell motility, and percentage of primary and secondary sperm abnormalities or ejaculates were not significantly affected by treatment of stallions with PGF2α before semen collection. All treated stallions exhibited a pronounced sweating response to the drug. During the experiment, two of the six stallions masturbated within 20 to 30 minutes after PGF2α treatment without achieving an erection. |
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