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Loss of the zona pellucida-binding protein 2 (Zpbp2) gene in mice impacts airway hypersensitivity and lung lipid metabolism in a sex-dependent fashion |
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| Authors: | Kanagaratham Cynthia Chiwara Victoria Ho Bianca Moussette Sanny Youssef Mina Venuto David Jeannotte Lucie Bourque Guillaume de Sanctis Juan Bautista Radzioch Danuta Naumova Anna K |
| Institution: | 1.Department of Human Genetics, McGill University, Montreal, QC, Canada ;2.The Research Institute of the McGill University Health Centre, Montreal, QC, Canada ;3.McGill University and Genome Quebec Innovation Centre, Montreal, QC, Canada ;4.Département de Biologie moléculaire, Biochimie medicale & Pathologie, Faculté de médecine, Université Laval, Québec, QC, Canada ;5.Centre de recherche sur le cancer de l’Université Laval, CRCHU de Québec-Université Laval, L’H?tel-Dieu de Québec, Québec, QC, Canada ;6.Institute of Immunology, Faculty of Medicine, Universidad Central de Venezuela, Sabana Grande, Caracas, Venezuela ;7.Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, QC, Canada ;8.Infectious Diseases and Immunity in Global Health Program (IDIGH), The Research Institute of the McGill University Health Centre, Montreal, QC, Canada ;9.Department of Obstetrics and Gynecology, McGill University, Montreal, QC, Canada ; |
| Abstract: | Mammalian Genome - The human chromosomal region 17q12–q21 is one of the best replicated genome-wide association study loci for childhood asthma. The associated SNPs span a large genomic... |
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