Diet influences the intake target and mitochondrial functions of Drosophila melanogaster males |
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Authors: | Nicolas Pichaud Marie Messmer Carolina C Correa J William O Ballard |
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Institution: | 1. School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, New South Wales 2052, Australia;2. Département de Biologie Intégrative, Université du Québec à Rimouski, Rimouski, QC, Canada |
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Abstract: | In this study, we examine the dietary protein to carbohydrate ratio (P:C) on the mitochondrial functions of two Drosophila melanogaster mtDNA haplotypes. We investigated multiple physiological parameters on flies fed with either 1:12 P:C or 1:3 P:C diets. Our results provide experimental evidence that a specific haplotype has a reduction of complex I activity when the flies are fed with the 1:12 P:C diet. This study is of particular importance to understand the influence of diet on mitochondrial evolution in invasive and broadly distributed species including humans. |
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