The genome of Mycobacterium leprae: a minimal mycobacterial gene set |
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Authors: | Vissa V D Brennan P J |
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Institution: | 1. Department of Microbiology, Colorado State University, Fort Collins, CO, 80523, USA
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Abstract: | Comparison of the recently sequenced genome of the leprosy-causing pathogen Mycobacterium leprae with other mycobacterial genomes reveals a drastic gene reduction and decay in M. leprae affecting many metabolic areas, exemplified by the retention of a minimal set of genes required for cell-wall biosynthesis. |
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