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Synthetic insulin-like growth factor II |
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| Authors: | C H Li D Yamashiro R G Hammonds M Westphal |
| Affiliation: | Laboratory of Molecular Endocrinology University of California San Francisco, CA 94143, USA |
| Abstract: | Human insulin-like growth factor II with 67 amino acid residues and three disulfide bridges has been synthesized by the solid-phase method. Homogeneity of the synthetic product is ascertained by chromatofocusing, high performance liquid chromatography and amino acid analysis. In both radioimmunoassay and radioreceptor assay, the synthetic product is indistinguishable from the natural hormone. |
| Keywords: | Sm-C somatomedin-C IGF insulin-like growth factor HPLC high performance liquid chromatography RIA radioimmunoassay RRA radioreceptor assay |
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