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Single non-inactivating K+ channels in the myotubes of the chick embryo in tissue culture
Authors:L Vyklicky  L Vyklicky  F Vyskocil  E Ujec  J Michl  V Vlachová
Abstract:Single-channel K+ currents were studied in the myotubes from the chick embryo grown in tissue culture for 4--9 days by employing the patch clamp technique. The "cell attached" configuration was used and the pipette was filled with a solution containing 3 mmol.l-1 K+. The channels exhibited a high conductance of approximately 90 pS and the probability of finding them open increased by an e-fold factor for 13 mV depolarization for low levels of activity. The channels did not inactivate during long-lasting depolarization. These channels have been suggested to contribute to delayed rectification.
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