In vitro antidiabetic,antioxidant, antimicrobial,and cytotoxic activity of Murraya koenigii leaf extract intercedes ZnO nanoparticles |
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| Authors: | Avinash Sharma Rupak Nagraik Baskar Venkidasamy Azhar Khan Kanika Dulta Pankaj Kumar Chauhan Deepak Kumar Dong-Soo Shin |
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| Affiliation: | 1. Faculty of Applied Sciences and Biotechnology, Shoolini University, Solan, India;2. Department of Biotechnology, Sri Shakthi Institute of Engineering and Technology, Coimbatore, Tamil Nadu, India;3. Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan, India;4. Department of Chemistry, Changwon National University, Changwon, South Korea |
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| Abstract: | Nanotechnology is an emerging field with tremendous potential and usage of medicinal plants and green preparation of nanoparticles (NPs) is one of the widely explored areas. These have been shown to be effective against different biological activities such as diabetes mellitus, cancer, antioxidant, antimicrobial, etc. The current studies focus on the green synthesis of zinc NPs (ZnO NPs) from aqueous leaf extract of Murraya koenigii (MK). The synthesized Murraya koeingii zinc oxide NPs (MK ZnO NPs) were characterized using UV–visible spectroscopy, dynamic light scattering (DLS), Fourier transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), energy-dispersive spectrum (EDS) and cyclic voltammetry (CV). The synthesized MK ZnO NPs were evaluated for their in vitro antidiabetic, antioxidant, antimicrobial, and cytotoxic activity. They demonstrated significant antidiabetic and cytotoxic activity, as well as moderate free-radical scavenging and antibacterial activity. |
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| Keywords: | antibacterial and cytotoxic activity antidiabetic activity green synthesis Murraya koenigii zinc oxide nanoparticles |
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