An improved total synthesis of triciribine: a tricyclic nucleoside with antineoplastic and antiviral properties |
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Authors: | Porcari Anthony R Townsend Leroy B |
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Affiliation: | Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA. anthony.porcari@pfizer.com |
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Abstract: | We describe an efficient total synthesis of triciribine, a tricyclic nucleoside with antineoplastic and antiviral properties, starting from 4-amino-6-bromo-5-cyanopyrrolo[2,3-d]pyrimidine. |
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