Effects of amphetamine on the development of MTV-induced mammary tumors in female mice. |
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Authors: | M Freire-Garabal M J Nú?ez J L Balboa J A Suárez A Gallego A Belmonte |
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Institution: | Department of Pharmacology, School of Medicine, University of Santiago, Spain. |
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Abstract: | Female C3H/He mice carrying the mammary tumor virus (MTV) were monitored for mammary tumor incidence and latent periods while submitted to a daily subcutaneous injection with amphetamine (0,4 mg/kg/day). Results show that amphetamine caused an increase in incidence and a decrease in latency of tumors compared with placebo. There was also appreciated a correlation with the lethality of mice. |
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