Abstract: | Testes from mouse and rat embryos were cultured in vitro in the presence of 14C-sodium acetate and luteinizing hormone or chorionic gonadotrophin. There is an increase in testosterone and androstenedione synthesis from sodium acetate under both treatments. Sensitivity to gonadotrophins exists already at a relatively early stage, when the testis, through testosterone secretion, is building up the genital tract. But the role of the hypophysis in normal androgen secretion will have to be proven. |