| 丙酮丁醇梭菌的遗传操作系统 |
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| 引用本文： | 董红军,张延平,李寅.丙酮丁醇梭菌的遗传操作系统[J].生物工程学报,2010,26(10):1372-1378. |
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| 作者姓名： | 董红军 张延平 李寅 |
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| 作者单位： | 中国科学院微生物研究所,北京,100101 |
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| 基金项目： | 国家高技术研究发展计划 (863计划) (No. 2006AA02Z237) 资助。 |
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| 摘 要： | 丙酮丁醇梭菌是极具潜力的替代燃料——生物丁醇的合成菌,受到各国研究者的普遍关注。丙酮丁醇梭菌菌株改造是生物丁醇产业化进程中的一项重要工作,其中遗传操作是核心内容之一。以下对丙酮丁醇梭菌的遗传操作系统的发展历史、种类和原理进行了综述,分析了目前几种遗传操作系统的局限性,并对其发展进行了展望。
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| 关 键 词： | 丙酮丁醇梭菌，丁醇，菌株改造，遗传操作系统 |
| 收稿时间： | 2010/6/15 0:00:00 |
Genetic modification systems for Clostridium acetobutylicum |
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| Hongjun Dong,Yanping Zhang and Yin Li.Genetic modification systems for Clostridium acetobutylicum[J].Chinese Journal of Biotechnology,2010,26(10):1372-1378. |
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| Authors: | Hongjun Dong Yanping Zhang and Yin Li |
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| Institution: | Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China;Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China;Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China |
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| Abstract: | Clostridium acetobutylicum, a biofuel-butanol producer, has attracted worldwide interests. Strain improvement is important for the process of biobutanol industrialization where efficient genetic modification systems are essential. In this review, the history of genetic modification systems of C. acetobutylicum was introduced, and the types and principles of these systems and their disadvantages are summarized and analysed. The development of updated genetic modification systems for C. acetobutylicum is also proposed. |
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| Keywords: | Clostridium acetobutylicum butanol strain improvement genetic modification systems |
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