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Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
Affiliation:1. Department of Urology, SUNY Upstate Medical University, Syracuse, NY 13210, USA;2. Upstate Cancer Center, SUNY Upstate Medical University, Syracuse, NY 13210, USA;3. Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, NY 13210, USA;4. Biochemistry and Biomedicine, School of Life Sciences, University of Sussex, Brighton, UK;5. School of Cancer and Pharmaceutical Sciences, Institute of Pharmaceutical Science, King’s College London, London SE1 9NQ, UK;6. Genome Damage and Stability Centre, University of Sussex, Brighton BN1 9RQ, UK
Abstract:
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  • Keywords:Hsp90  chaperone  co-chaperone  phosphorylation  chaperone code  Ulk1  atg1  autophagy  CP: Molecular biology
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