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Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design |
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| Institution: | 1. Department of Computer Science, Duke University, Durham, NC, USA;2. Program in Computational Biology & Bioinformatics, Duke University, Durham, NC, USA;3. Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA;4. Department of Biochemistry, Duke University, Durham, NC, USA;5. Department of Mathematics, Duke University, Durham, NC, USA;6. Department of Chemistry, Duke University, Durham, NC, USA |
| Abstract: |  |
| Keywords: | antibody improvement broadly neutralizing antibody HIV OSPREY protein design structural biology antibody design provable algorithms CP: Microbiology CP: Immunology |
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