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Tumor-specific CD4 T cells instruct monocyte fate in pancreatic ductal adenocarcinoma
Affiliation:1. Center for Immunology, University of Minnesota, Minneapolis, MN 55414, USA;2. Department of Integrative Biology and Physiology, University of Minnesota, Minneapolis, MN 55414, USA;3. Department of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55414, USA;4. Computer Technologies Laboratory, ITMO University, Saint-Petersburg, Russia;5. National Medical Research Center, Saint-Petersburg, Russia;6. Masonic Cancer Center and University of Minnesota Medical School, Minneapolis, MN 55414, USA;7. Center for Genome Engineering, University of Minnesota Medical School, Minneapolis, MN 55414, USA
Abstract:
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  • Keywords:pancreatic cancer  PDA  T cells  macrophage  CD4 T cells  IFNg  CD40  immunotherapy  PD-L1  CCR2  CP: Cancer  CP: Immunology
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