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Prox2 and Runx3 vagal sensory neurons regulate esophageal motility
Institution:1. Developmental Biology/Signal Transduction, Max Delbrück Center for Molecular Medicine, Berlin, Germany;2. NeuroCure Cluster of Excellence, CharitéUniversitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany;3. Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany;4. Department of Otolaryngology - Head & Neck Surgery, University of Missouri School of Medicine, Columbia, MO, USA;5. The First Affiliated Hospital, Jinan University, Guangzhou, China;6. Howard Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA;7. Development and Function of Neural Circuits, Max Delbrück Center for Molecular Medicine, Berlin, Germany;8. Immune Regulation and Cancer, Max Delbrück Center for Molecular Medicine, Berlin, Germany;9. Systems Biology Imaging, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany;10. Institut de Biologie de l’ENS (IBENS), Inserm, CNRS, École normale supérieure, PSL Research University, Paris, France;11. Genome Engineering & Disease Models, Max Delbrück Center for Molecular Medicine, Berlin, Germany;12. Molecular Physiology of Somatic Sensation, Max Delbrück Center for Molecular Medicine, Berlin, Germany
Abstract:
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  • Keywords:vagus nerve  vagal afferents  single-cell RNA sequencing  esophagus  peristalsis  mechanoreceptors  mechanosensation  motility  homeostasis  digestion
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