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Antimony to Cure Visceral Leishmaniasis Unresponsive to Liposomal Amphotericin B |
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| Authors: | Gloria Morizot Romain Jouffroy Albert Faye Paul Chabert Katia Belhouari Ruxandra Calin Caroline Charlier Patrick Miailhes Jean-Yves Siriez Oussama Mouri Hélène Yera Jacques Gilquin Roland Tubiana Fanny Lanternier Marie-France Mamzer Christophe Legendre Dominique Peyramond Eric Caumes Olivier Lortholary Pierre Buffet |
| Abstract: | We report on 4 patients (1 immunocompetent, 3 immunosuppressed) in whom visceral leishmaniasis had become unresponsive to (or had relapsed after) treatment with appropriate doses of liposomal amphotericin B. Under close follow-up, full courses of pentavalent antimony were administered without life-threatening adverse events and resulted in rapid and sustained clinical and parasitological cure. |
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