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Inter-organ insulin-leptin signal crosstalk from the liver enhances survival during food shortages
Affiliation:1. Department of Metabolism and Diabetes, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan;2. Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Bunkyo, Tokyo 113-8510, Japan;3. Department of Gastroenterology, Faculty of Medicine, Yamagata University, Yamagata, Yamagata 990-9585, Japan;4. Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan
Abstract:
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  • Keywords:liver  insulin  insulin receptor  food intake  energy expenditure  brown adipose tissue  thermogenesis  soluble leptin receptor  food restriction  survival  CP: Metabolism
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