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SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions
Affiliation:1. Howard Hughes Medical Institute, Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA;2. National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China;3. Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA;4. Initiative for Genome Editing and Neurodegeneration, Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA;5. Precision Medicine Institute, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
Abstract:
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  • Keywords:polycomb  rixosome  SUMO  ubiquitin  deSUMOylation  deubiquitination  gene silencing  heterochromatin  epigenetics  SENP3  USP7  CP: Molecular biology
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