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Tumor eradication by hetIL-15 locoregional therapy correlates with an induced intratumoral CD103intCD11b+ dendritic cell population
Affiliation:1. Human Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA;2. Department of Chemical Biology, National Hellenic Research Foundation, 11635 Athens, Greece;3. Basic Science Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD 21702, USA;4. Department of Pharmacology, Faculty of Medicine, University of Thessaly, 41500 Larissa, Greece;5. Vaccine Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA;6. Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD 21702, USA;7. Laboratory Animal Sciences Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD 21702, USA;8. Human Retrovirus Pathogenesis Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA
Abstract:
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  • Keywords:immonotherapy  mouse models  interleukin-15  IL-15  cytokines  breast cancer  dendritic cells  T cell memory  CP: Cancer  CP: Immunology
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