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Ventral tegmental area astrocytes modulate cocaine reward by tonically releasing GABA
Institution:1. Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA;2. Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA;1. Department of Experimental Neuroendocrinology, Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna St, 31-343 Krakow, Poland;2. Department of Anatomy, Jagiellonian University Medical College, 12 Kopernika St, 31-034 Krakow, Poland;1. Biomedical Engineering, Georgia Institute of Technology & Emory University, Atlanta, GA, USA;2. Electrical and Computer Engineering, Georgia Institute of Technology & Emory University, Atlanta, GA, USA;3. Bioengineering, UCSF – UC Berkeley Joint PhD Program, San Francisco, CA, USA;1. Aix Marseille University, INSERM, INMED (UMR1249), Turing Centre for Living systems, Marseille, France;2. Department of Cell and Developmental Biology, University College London, London, UK;3. Department of Psychology, Durham University, Durham, UK;1. Department of Psychiatry and Behavioral Sciences, State University of New York Upstate Medical University, Syracuse, NY 13210, USA;2. Neuroscience Graduate Program, State University of New York Upstate Medical University, Syracuse, NY 13210, USA;3. Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA;4. Neuroscience Program, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA;5. Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA;6. Department of Neuroscience and Physiology, State University of New York Upstate Medical University, Syracuse, NY 13210, USA;1. Department of Experimental Psychology, University of Oxford, Oxford OX2 6GG, UK;2. Oxford Centre for Human Brain Activity, Wellcome Centre for Integrative Neuroimaging, Department of Psychiatry, University of Oxford, Oxford OX3 7JX, UK;3. Institute for Brain and Behavior Amsterdam, Department of Experimental and Applied Psychology, Vrije Universiteit Amsterdam, Amsterdam 1081BT, the Netherlands;1. Zilkha Neurogenetic Institute, Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA;2. Graduate Program in Biological and Biomedical Sciences, University of Southern California, Los Angeles, CA 90089, USA;3. Center for Neural Circuits and Sensory Processing Disorders, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA;4. McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Abstract:
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  • Keywords:cocaine reward  astrocytes  tonic inhibition  volume-regulated anion channel  addiction
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