Epidemiology of laryngeal cancer in Brazil: Historical data from 2000 to 2019 |
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| Institution: | 1. Department of Radiotherapy, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Pernambuco, Brazil;2. Department of Education and Research, Hospital de Câncer de Pernambuco, Recife, Pernambuco, Brazil;3. Department of Head and Neck Surgery, Hospital de Câncer de Pernambuco, Recife, Pernambuco, Brazil;4. Department of Oncology, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Pernambuco, Brazil;5. Department of Pneumology, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Pernambuco, Brazil;6. Clinical Research Division, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Pernambuco, Brazil;1. Division of Epidemiology, Department of Health Informatics and Public Health, Tohoku University School of Public Health, Graduate School of Medicine, Sendai, Japan;2. Division of Epidemiology, Miyagi Prefectural Cancer Research Center, Natori, Japan;3. Miyagi Cancer Society, Sendai, Japan;1. Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA, USA;2. Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA, USA;3. Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA;1. Department of Epidemiology and Biostatistics, School of Public Health, Indiana University Bloomington, Bloomington, IN, USA;2. Department of Environmental and Occupational Health, School of Public Health, Indiana University, Bloomington, IN, USA;3. Department of Chronic Disease Epidemiology, Yale School of Public Health, Yale University, New Haven, CT, USA;4. Department of Translational Sciences Section, School of Nursing, University of California, Los Angeles, CA, USA;5. Department of Family, Population and Preventive Medicine, Renaissance School of Medicine, Stony Brook University, NY, USA;6. Department of Medical Oncology, The Lundquist Institute, Torrance, CA, USA;7. Department of Preventive Medicine, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA;8. Division of Epidemiology, Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN, USA;1. Brown School, Washington University in St. Louis, St. Louis, MO, USA;2. Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA;3. Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO, USA;4. Rollins School of Public Health, Emory University, Atlanta, GA, USA;1. Department of Internal Medicine, Jackson Memorial Hospital / University of Miami Health System, FL, USA;2. The Population Registry of Cancer of the Metropolitan Area of Bucaramanga, Universidad Autónoma de Bucaramanga, Colombia;3. Department of Clinical Epidemiology and Biostatistics, Pontificia Universidad Javeriana, Bogota, Colombia;4. University of Miami Miller School of Medicine and Sylvester Comprehensive Cancer Center, FL, USA |
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| Abstract: | IntroductionTo determine the incidence, morbidity, and mortality rate of laryngeal cancer in two decades and its epidemiological, clinical, and histological characteristics by sex in Brazil.MethodsThis ecological study used three reliable sources of secondary data: population- and hospital-based cancer registries and the national mortality database. All data available from 2000 to 2019 were considered.ResultsThe incidence of male laryngeal cancer decreased from 9.20 to 4.95 per 100,000 from 2000 to 2018, while mortality slightly decreased from 3.37 to 3.30 per 100,000 from 2000 to 2019. In the same period, the female incidence decreased from 1.26 to 0.48 per 100,000; however, mortality slightly increased from 0.34 to 0.36 per 100,000. Of 221,566 individuals with head and neck cancer, 27 % presented laryngeal cancer. The median age was 61 years (54−69), and most individuals were male (86.6 %), smokers (66.2 %), diagnosed with locally advanced cancer (66.7 %), and squamous cell carcinoma as the main histological type (93.2 %). Male tended to be older (p < 0.001), white (p < 0.001), smokers (p < 0.001), and present late treatment initiation (p < 0.001) and early death (p < 0.001) compared with female.ConclusionThe male laryngeal cancer affected mainly at productive age but with a decreased incidence, probably due to a reduction in smoking habit. However, mortality did not change, which may be explained by the late diagnosis and lack of access to radiotherapy. |
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| Keywords: | Incidence Mortality Laryngeal cancer Brazil Gender |
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