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Asymmetric cell division safeguards memory CD8 T cell development
Affiliation:1. Institute of Microbiology, ETH Zurich, Vladimir-Prelog-Weg 4, 8093 Zurich, Switzerland;2. Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058 Basel, Switzerland;3. Department of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland;4. The Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Roosevelt Drive, Oxford OX3 7FY, UK;5. Center for Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands;6. Department of Metabolic Disease Research, Biomedical Research Center of the Slovak Academy of Sciences, Dubravska cesta 9, 845 05 Bratislava, Slovakia;7. Department of Health Sciences and Technology, ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
Abstract:
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  • Keywords:asymmetric cell division  CD8 T cell differentiation  lineage tracing  single cell tracking  CD8 T cell memory  T cell receptor signaling strength  fate diversification  CP: Immunology  CP: Cell biology
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