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Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging
Institution:1. Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA;2. Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA, USA;3. Department of Neurology, UCLA, Los Angeles, CA, USA;4. Department of Genetics, Stanford University, Stanford, CA, USA;5. Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA;6. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA;7. Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA;8. Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA;9. Department of Medicine, Stanford University, Stanford, CA, USA;10. Greenstone Biosciences, Palo Alto, CA, USA;11. Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA;12. Neurology Service, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA;13. Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, UCLA, Los Angeles, CA, USA
Abstract:
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  • Keywords:exercise  skeletal muscle  muscle stem cells  myofibers  neural stem cells  subventricular zone  hematopoietic stem cells  aging  inflammation  scRNA-seq
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