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Representation and control of pain and itch by distinct prefrontal neural ensembles
Institution:1. School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China;2. Department of Anatomy and Physiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;3. Songjiang Hospital and Songjiang Research Institute, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China;4. Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai 201210, China;5. Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai 200030, China;1. Developmental Biology/Signal Transduction, Max Delbrück Center for Molecular Medicine, Berlin, Germany;2. NeuroCure Cluster of Excellence, CharitéUniversitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany;3. Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany;4. Department of Otolaryngology - Head & Neck Surgery, University of Missouri School of Medicine, Columbia, MO, USA;5. The First Affiliated Hospital, Jinan University, Guangzhou, China;6. Howard Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA;7. Development and Function of Neural Circuits, Max Delbrück Center for Molecular Medicine, Berlin, Germany;8. Immune Regulation and Cancer, Max Delbrück Center for Molecular Medicine, Berlin, Germany;9. Systems Biology Imaging, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany;10. Institut de Biologie de l’ENS (IBENS), Inserm, CNRS, École normale supérieure, PSL Research University, Paris, France;11. Genome Engineering & Disease Models, Max Delbrück Center for Molecular Medicine, Berlin, Germany;12. Molecular Physiology of Somatic Sensation, Max Delbrück Center for Molecular Medicine, Berlin, Germany;1. Division of Cognitive Neurobiology, Center for Brain Research, Medical University of Vienna, 1090 Vienna, Austria;1. Department of Neuroscience, Mortimer B. Zuckerman Mind Brain Behavior Institute, The Kavli Institute for Brain Science, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10027, USA;1. Department of Neurobiology, Duke University School of Medicine, Durham, NC 27710, USA;2. Edmond & Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel;1. Shenzhen Key Lab of Neuropsychiatric Modulation, Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Center for Excellence in Brain Science and Intelligence Technology, the Brain Cognition and Brain Disease Institute, Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China;2. Department of Electrical Engineering, City University of Hong Kong, Hong Kong 999077, China;3. University of Science and Technology of China, Hefei 230026, China;4. University of Chinese Academy of Sciences, Beijing 100049, China;1. State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China;2. PKU-IDG/McGovern Institute for Brain Research, Beijing 100871, China;3. Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China;4. Division of Medicinal Chemistry, Faculty of Science, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands;5. Chinese Institute for Brain Research, Beijing 102206, China;6. National Biomedical Imaging Center, Peking University, Beijing 100871, China
Abstract:
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  • Keywords:medial prefrontal cortex  pain  itch  neural circuit  neural ensembles
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