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AMPK activation protects against prostate cancer by inducing a catabolic cellular state
Affiliation:1. MRC London Institute of Medical Sciences, Hammersmith Hospital Campus, Imperial College London, London W12 0NN, UK;2. Institute of Clinical Sciences, Imperial College London, London, UK;3. Imperial Centre for Translational and Experimental Medicine, Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, London, UK;4. Department of Biomedical Sciences and Cornell Stem Cell Program, Cornell University, Ithaca, NY, USA;5. Biomolecular Medicine, Division of Systems Medicine, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, UK
Abstract:
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  • Keywords:AMPK  cell cycle regulation  fatty acid oxidation  high-fat diet  lipogenesis  PGC1α  prostate cancer  metabolism  metastasis  mitochondria  CP: Cancer  CP: Metabolism
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