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Neurons require glucose uptake and glycolysis in vivo
Affiliation:1. Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA;2. Department of Physical Therapy and Rehabilitation Science, San Francisco, CA 94158, USA;3. Department of Radiology and Biomedical Imaging, San Francisco, CA 94158, USA;4. Graduate Program in Biomedical Sciences, University of California San Francisco, San Francisco, CA 94143, USA;5. Graduate Program in Neuroscience, University of California San Francisco, San Francisco, CA 94158, USA;6. UCSF/UCB Graduate Program in Bioengineering, University of California San Francisco, San Francisco, CA 94158, USA;7. Koch Institute for Integrative Cancer Research and the Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;8. Institute for Neurodegenerative Diseases, University of California San Francisco, San Francisco, CA, USA;9. Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA;10. Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA;11. Vanderbilt Center for Immunobiology, Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA;12. Dana-Farber Cancer Institute, Boston, MA 02115, USA
Abstract:
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  • Keywords:neuronal glucose metabolism  brain energy  bioenergetics  glycolysis  glucose transporter  pyruvate kinase  hyperpolarized magnetic resonance spectroscopic imaging  metabolomics  galactose metabolism  CP: Neuroscience
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