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Co-option of endogenous retroviruses through genetic escape from TRIM28 repression |
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| Institution: | 1. Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London E1 2AT, UK;2. Bill Lyons Informatics Centre, UCL Cancer Institute, London WC1E 6DD, UK;3. Department of Genetics and Genome Sciences, University of Connecticut Health Center, The Jackson Laboratory for Genomic Medicine, Connecticut, JAX CT, Farmington, CT 06032, USA;4. MRC-University of Glasgow Centre for Virus Research, Glasgow G611QH, UK |
| Abstract: |  |
| Keywords: | co-option exaptation endogenous retroviruses ERVs intracisternal A-type particles IAPs retrotransposon TRIM28 epigenetic silencing KRAB-zinc finger proteins enhancers retrotransposition cancer CP: Developmental biology CP: Stem cell research |
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