| 转谷氨酰胺酶的分子生物学与基因工程 |
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| 引用本文： | 王莉,常忠义,李平作. 转谷氨酰胺酶的分子生物学与基因工程[J]. 生物技术通讯, 2004, 15(5): 492-494 |
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| 作者姓名： | 王莉 常忠义 李平作 |
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| 作者单位： | 1. 华东师范大学,生命科学学院,上海,200062
2. 上海中科伍佰豪生物工程有限公司,上海,200233 |
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| 摘 要： | 来源于微生物特别是轮枝链霉菌的转谷氨酰胺酶是一种重要的酶制剂，在食品工业中有着广泛的应用前景。本综述了近年来对转谷氨酰胺酶的分子生物学研究成果，以及对其进行基因工程改造的最新进展，讨论了其进一步的研究发展方向。笔认为采用基因工程生产重组转谷氨酰胺酶是解决目前酶价高昂和来源困难问题的一个大有希望的办法。
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| 关 键 词： | 分子生物学研究 基因工程 研究发展 来源 综述 微生物 困难 转谷氨酰胺酶 酶制剂 食品工业 |
| 文章编号： | 1009-0002(2004)05-0492-03 |
| 修稿时间： | 2004-02-26 |
The molecular biology and genetic engineering of transglutaminase |
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| WANG li,CHANG Zhong-yi,LI Ping-zuo. Life Science College of East China Normal University,Shanghai . The molecular biology and genetic engineering of transglutaminase[J]. Letters in Biotechnology, 2004, 15(5): 492-494 |
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| Authors: | WANG li CHANG Zhong-yi LI Ping-zuo. Life Science College of East China Normal University Shanghai |
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| Affiliation: | WANG li1,CHANG Zhong-yi1,LI Ping-zuo21. Life Science College of East China Normal University,Shanghai 200062,2. Shanghai Wubaihao Biotechnology Research and Development Ltd.,Shanghai 200233,China |
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| Abstract: | The microbial transglutaminase(TGase) especially which come from Streptoverticillium is an important enzyme. It is widely used in food industry. The recent progresses in the study of the enzyme, especially on the molecular biology and genetic engineering of it were summarized here. In addition, the future development is discussed in this paper. We consider that with the tool of genetic engineering, we'll soon gain a recombine bacterium, which can highly and activated expression TGase. |
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| Keywords: | transglutaminase molecular biology genetic engineering |
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