13C-n.m.r. studies of the conformational changes in proline oligomers brought about by lithium and calcium salts |
| |
Authors: | Ch Pulla Rao P Balaram C.N.R Rao |
| |
Affiliation: | Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore 560012, India |
| |
Abstract: | A detailed 13C-n.m.r. investigation has been carried out on the conformational changes in proline oligomers brought about by interaction with lithium and calcium perchlorates. Interaction of lithium and calcium salts with Piv-(Pro)n-OMe, n = 2, 4 and 5 results in trans-cis isomerization. In the case of pentaproline, metal salts also give rise to other trans-isomers caused by the rotation about the CαC(O) bond (Ψ, cis). Calcium salts seem to stabilize cis'-isomers and produce effects somewhat different from those of lithium salts. |
| |
Keywords: | Peptides proline oligomers peptide conformation salt effects |
本文献已被 ScienceDirect 等数据库收录! |