| 水朝阳旋覆花化学成分的研究 |
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| 引用本文： | 常睿洁,覃江江,成向荣,金慧子,张卫东. 水朝阳旋覆花化学成分的研究[J]. 天然产物研究与开发, 2012, 24(3): 291-297,328 |
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| 作者姓名： | 常睿洁 覃江江 成向荣 金慧子 张卫东 |
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| 作者单位： | 1. 上海交通大学药学院,上海,200240
2. 上海交通大学药学院,上海200240;第二军医大学药学院,上海200433 |
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| 基金项目： | Foundation,Item:This,research,project,was,supported,by,program,NCET,Foundation,NSFC,(81102778),and,the,Scientific,Foundation,of,Shanghai,China |
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| 摘 要： | 从水朝阳旋覆花(Inula helianthus-aquatica)地上部分分离得到24个化合物,经波谱数据分析分别鉴定为aromaticin(1),8-epi-helenalin(2),bigelovin(3),2,3-dihydroaromaticin(4),carpesiolin(5),ergolide(6),inuchinenolide C(7),6α-acetoxy-isoinuviscolide(8),8-epi-inuviscolide(9),inuchinenolide B(10),tomentosin(11),11α,13-dihydrotomentosin(12),inuchinenolide A(13),4H-tomentosin(14),11β,13-dihydro-4H-tomentosin(15),11-epi-sundiversifolide(16),sundiversifolide(17),8,9,10-三羟基百里香酚(18),10-羟基-8,9-双氧亚异丙基百里香酚(19),8,10-二羟基-9-异丁酰百里香酚(20),8-羟基-9,10-二异丁酰百里香酚(21),8-羟基-9-异丁酰-10-(2-甲基丁酰)百里香酚(22),8,9-环氧-9,10-二异丁酰百里香酚(23)和8,9-环氧-3-异丁酰-10-(2-甲基丁酰)百里香酚(24)。除了化合物1～6外,其他化合物均为首次从该植物中分离得到。
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| 关 键 词： | 旋覆花属 水朝阳旋覆花 倍半萜 单萜 |
Chemical Constituents from Inula helianthus-aquatica |
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| CHANG Rui-jie , QIN Jiang-jiang , CHENG Xiang-rong , JIN Hui-zi , ZHANG Wei-dong. Chemical Constituents from Inula helianthus-aquatica[J]. Natural Product Research and Development, 2012, 24(3): 291-297,328 |
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| Authors: | CHANG Rui-jie QIN Jiang-jiang CHENG Xiang-rong JIN Hui-zi ZHANG Wei-dong |
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| Affiliation: | 1,2* 1School of Pharmacy,Shanghai Jiao Tong University,Shanghai 200240,China; 2School of Pharmacy,Second Military University,Shanghai 200433,China |
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| Abstract: | Twenty-four compounds were isolated from the aerial parts of Inula helianthus-aquatica.On the basis of spectral data,their structures were identified as aromaticin(1),8-epi-helenalin(2),bigelovin(3),2,3-dihydroaromaticin(4),carpesiolin(5),ergolide(6),inuchinenolide C(7),6α-acetoxy-isoinuviscolide(8),8-epi-inuviscolide(9),inuchinenolide B(10),tomentosin(11),11α,13-dihydrotomentosin(12),inuchinenolide A(13),4H-tomentosin(14),11β,13-dihydro-4H-tomentosin(15),11-epi-sundiversifolide(16),sundiversifolide(17),8,9,10-trihydroxythymol(18),10-hydroxy-8,9-dioxyisopropylidenethymol(19),8,10-dihydroxy-9-isobutyryloxythymol(20),8-hydroxy-9,10-diisobutyryloxythymol(21),8-hydroxy-9-isobutyryloxy-10-(2-methylbutanoyl)thymol(22),8,9-epoxy-3,10-diisobutyryloxythymol(23),and 8,9-epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol(24).All the compounds except 1-6 were isolated from this plant for the first time. |
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| Keywords: | Inula Inula helianthus-aquatica sesquiterpene monoterpenes |
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