Dynamic filtration of the expression pattern variability of Drosophila zygotic segmentation genes |
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| Authors: | S. Yu. Surkova E. M. Myasnikova J. Reinitz M. G. Samsonova |
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| Affiliation: | (1) Department of Computer Biology, St. Petersburg State Polytechnic University, St. Petersburg, Russia;(2) Department of Applied Mathematics and Statistics and Center for Developmental Genetics, Stony Brook University, Stony Brook, NY, USA |
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| Abstract: | Analysis of the quantitative data obtained by processing the confocal images showed that the initial variability of the expression pattern of Drosophila zygotic segmentation genes was strongly reduced by the onset of gastrulation. The following variability components were studied: the range of gene expression intensity in different embryos, the time and succession of the formation of expression domain, types of formation, and domain positioning. At the level of zygotic genes, the positioning error proved to be dynamically filtered with time. |
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| Keywords: | Drosophila segmentation genes variability expression positioning error |
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