The induction of suppressor T cells by lipopolysaccharide in human peripheral blood lymphocyte cultures in the presence of fetal calf serum |
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| Authors: | R A Miller S Gartner H S Kaplan |
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| Institution: | Princess Margaret Children''s Medical Research Foundation, Clinical Immunology Unit, Princess Margaret Hospital for Children, Subiaco, Perth, Western Australia, Australia |
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| Abstract: | Alveolar macrophages (AM) were collected by repeated endobronchial lavage from mice, rats, guinea pigs, and rabbits, and titrated into cultures of mitogen-stimulated syngeneic or autochthonous lymphocytes. Significant species differences were detected in regard to AM activity in the cultures. AM from guinea pigs and mice stimulated PHA-induced lymphoproliferation, while those from rats and rabbits were inhibitory; blood or peritoneal macrophages were not inhibitory in any of the species examined. |
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| Keywords: | To whom reprint requests should be addressed |
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