Protein degradation: recognition of ubiquitinylated substrates |
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Authors: | Hartmann-Petersen Rasmus Gordon Colin |
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Institution: | August Krogh Institute, University of Copenhagen, Universitetsparken 13, DK-2100 Copenhagen, Denmark. |
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Abstract: | A cell-free system has been developed in budding yeast that provides direct evidence that the Dsk2/Dph1, Rad23/Rhp23 and Rpn10/Pus1 multi-ubiquitin-binding proteins, long implicated in substrate recognition and presentation to the 26S proteasome, actually fulfil such a role. |
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