CARd: Carbon distribution analysis program for protein sequences |
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Authors: | Ekambaram Rajasekaran |
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Institution: | Department of Bioinformatics, School of Biotechnology and Health Sciences, Karunya University, Karunya Nagar, Coimbatore 641114. |
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Abstract: | Carbon distribution is responsible for stability and structure of proteins. Arrangement of carbon along the protein sequence is depends on how the amino acids are organized and is guided by mRNAs. An atomic level revision is important for understanding these codes. This will ultimately help in identification of disorders and suggest mutations. For this purpose a carbon distribution analysis program has been developed. This program captures the hydrophobic / hydrophilic / disordered regions in a protein. The program gives accurate results. The calculations are precise and sensitive to single amino acid resolution. This program is to help in mutational studies leading to protein stabilisation. |
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Keywords: | carbon distribution mutational study hydrophobic hydrophilic program protein disorder hydropathy |
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