Chaperones come of age |
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Authors: | Soti Csaba Csermely Péter |
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Institution: | Department of Medical Chemistry, Semmelweis University, Budapest, Hungary. |
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Abstract: | Chaperone function plays a key role in repairing proteotoxic damage, in the maintenance of cell architecture, and in cell survival. Here, we summarize our current knowledge about changes in chaperone expression and function in the aging process, as well as their involvement in longevity and cellular senescence. |
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