Maize streak virus-resistant transgenic maize: a first for Africa |
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Authors: | Shepherd Dionne N Mangwende Tichaona Martin Darren P Bezuidenhout Marion Kloppers Frederik J Carolissen Charlene H Monjane Adérito L Rybicki Edward P Thomson Jennifer A |
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Institution: | Department of Molecular and Cell Biology, University of Cape Town, Private Bag, Rondebosch 7701, South Africa; Division of Pharmacology, University of Cape Town, Observatory 7925, South Africa; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, South Africa; PANNAR (PTY) Limited, PO Box 19, Greytown 3250, South Africa |
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Abstract: | In this article, we report transgene-derived resistance in maize to the severe pathogen maize streak virus (MSV). The mutated MSV replication-associated protein gene that was used to transform maize showed stable expression to the fourth generation. Transgenic T2 and T3 plants displayed a significant delay in symptom development, a decrease in symptom severity and higher survival rates than non-transgenic plants after MSV challenge, as did a transgenic hybrid made by crossing T2 Hi-II with the widely grown, commercial, highly MSV-susceptible, white maize genotype WM3. To the best of our knowledge, this is the first maize to be developed with transgenic MSV resistance and the first all-African-produced genetically modified crop plant. |
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Keywords: | African biotechnology geminivirus maize streak virus maize streak virus-resistant maize maize yield improvement pathogen-derived resistance transgenic maize |
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