RNA-Binding Activity of the E1B 55-Kilodalton Protein from Human Adenovirus Type 5 |
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| Authors: | Jackie J. Horridge and Keith N. Leppard |
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| Affiliation: | Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom |
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| Abstract: | The human adenovirus 5 E1B 55-kDa protein is required for efficient nucleocytoplasmic transport of late viral mRNAs. This protein is shown to have RNA-binding activity which maps to a region of the protein with homology to a family of RNA-binding proteins and which has been shown previously to be essential for functionality of the protein in vivo. |
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